(* co-first author; # corresponding author)

 

Feng P#, Wu X, Erramilli SK, Paulo JA, Knejski P, Gygi SP, Kossiakoff AA, Rapoport TA#. A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel. Nature. 2022 Jun 29. doi: 10.1038/s41586-022-04903-x. LINK

Wu X#, Rapoport TA#. Cryo-EM structure determination of small proteins by nanobody-binding scaffolds (Legobodies). PNAS. 2021 Oct 12;118(41):e2115001118. LINK

Wu M#, Wu X. A kinetic view of clathrin assembly and endocytic cargo sorting. Curr Opin Cell Biol. 2021 Aug;71:130-138. LINK

Wu X, Rapoport TA#. Translocation of proteins through a distorted lipid bilayer. Trends Cell Biol. 2021 Jan 30;S0962-8924(21)00006-4. LINK

Sever N, Miličić G, Bodnar NO, Wu X, and Rapoport TA#. Mechanism of lamellar body formation by lung surfactant protein B. Mol Cell. 2021 Jan 7;81(1):49-66.e8. LINK

Wu X, Siggel M, Ovchinnikov S, Mi W, Svetlov V, Nudler E, Liao M, Hummer G, Rapoport TA#. Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science. 2020 Apr 24;368 (6489):eaaz2449. doi: 10.1126/science.aaz2449. LINK

Chung J, Wu X, Lambert T, Lai Z, Walther TC# and Farese RV Jr#. Lipid droplet assembly factor-1 and seipin form a lipid droplet assembly complex. Dev Cell. 2019 Dec 2;51(5):551-563.e7. LINK

Wu X, Cabanos C, Rapoport TA#. Structure of the post-translational protein translocation machinery of the ER membrane. Nature. 2019 Feb;566(7742):136-139. LINK

Wu X, Rapoport TA#. Mechanistic insights into ER-associated protein degradation. Curr Opin Cell Biol. 2018 Aug; 53:22-28. LINK

Baskin JM*, Wu X*, Christiano R, Oh MS, Schauder CM, Gazzerro E, Messa M, Baldassari S, Assereto S, Biancheri R, Zara F, Minetti C, Raimondi A, Simons M, Walther TC, Reinisch KM#, De Camilli P#.  The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane. Nat Cell Biol. 2016 Jan;18(1):132-8. LINK

Shen H, Giordano F, Wu Y, Chan J, Zhu C, Milosevic I, Wu X, Yao K, Chen B, Baumgart T, Sieburth D, De Camilli P#. Coupling between endocytosis and sphingosine kinase 1 recruitment. Nat Cell Biol. 2014 Jul;16(7):652-62. LINK

Wu X, Chi RJ, Baskin JM, Lucast L, Burd CG, De Camilli P, and Reinisch KM#. Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex. Dev Cell. 2014 Jan 13;28(1):19-29. LINK

Schauder CM, Wu X, Saheki Y, Narayanaswamy P, Torta F, Wenk MR, De Camilli P#, Reinisch KM#. Structure of a lipid-bound Extended-Synaptotagmin indicates a role in lipid transfer. Nature. 2014 Jun 26;510(7506):552-5. LINK

Shen D, Yuan H, Hutagalung A, Verma A, Kümmel D, Wu X, Reinisch KM, McNew JA, Novick P#. The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p. J Cell Biol. 2013 Aug 5; 202(3):509-26. LINK

Wu M#, Wu X, De Camilli P#. Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations. PNAS. 2013 Jan 22; 110(4):1339-44. LINK

Wu X, Bradley MJ, Cai Y, Kümmel D, De La Cruz EM, Barr FA, Reinisch KM#. Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. PNAS. 2011 Nov 15; 108 (46):18672-7. LINK

Wu X, Wu D, Lu Z, Chen W, Hu X, Ding Y#. A novel method for high-level production of TEV protease by superfolder GFP tag. J Biomed Biotechnol. 2009; 2009:591923. LINK